Ciglitazone—a human PPARγ agonist—disrupts dorsoventral patterning in zebrafish

Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation. While the role of PPARγ in adipogenesis and diabetes has been extensively studied, little is known about PPARγ function during early...

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Bibliographic Details
Main Authors: Vanessa Cheng, Subham Dasgupta, Aalekhya Reddam, David C. Volz
Format: Article
Language:English
Published: PeerJ Inc. 2019-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8054.pdf