Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white a...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-25766-2 |
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doaj-74f4186b66d4405aa52f8f0ea75e6eb12021-09-12T11:45:44ZengNature Publishing GroupNature Communications2041-17232021-09-0112111810.1038/s41467-021-25766-2Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissueXin Cui0Jia Jing1Rui Wu2Qiang Cao3Fenfen Li4Ke Li5Shirong Wang6Liqing Yu7Gary Schwartz8Huidong Shi9Bingzhong Xue10Hang Shi11Department of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityDepartment of Medicine, University of Maryland School of MedicineDepartment of Medicine, Albert Einstein College of MedicineGeorgia Cancer Center, Augusta UniversityDepartment of Biology, Georgia State UniversityDepartment of Biology, Georgia State UniversityActivation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white adipose beiging.https://doi.org/10.1038/s41467-021-25766-2 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Xin Cui Jia Jing Rui Wu Qiang Cao Fenfen Li Ke Li Shirong Wang Liqing Yu Gary Schwartz Huidong Shi Bingzhong Xue Hang Shi |
| spellingShingle |
Xin Cui Jia Jing Rui Wu Qiang Cao Fenfen Li Ke Li Shirong Wang Liqing Yu Gary Schwartz Huidong Shi Bingzhong Xue Hang Shi Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue Nature Communications |
| author_facet |
Xin Cui Jia Jing Rui Wu Qiang Cao Fenfen Li Ke Li Shirong Wang Liqing Yu Gary Schwartz Huidong Shi Bingzhong Xue Hang Shi |
| author_sort |
Xin Cui |
| title |
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue |
| title_short |
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue |
| title_full |
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue |
| title_fullStr |
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue |
| title_full_unstemmed |
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue |
| title_sort |
adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-09-01 |
| description |
Activation of brown adipose tissue thermogenesis increases energy expenditure and promotes weight loss in mice. Here the authors identify neurotrophic factor neurotrophin 3 (NT-3) as an adipokine that regulates sympathetic nervous system growth and innervation in adipose tissue and increases white adipose beiging. |
| url |
https://doi.org/10.1038/s41467-021-25766-2 |
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