Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurity in Lansoprazole

An unknown impurity in lansoprazole (2-[[[3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridyl] methyl] sulfinyl] benzimidazole) was detected by HPLC and was identified as des-(trifluoroethoxy) lansoprazole, an principal synthetic route indicative impurity of lansoprazole. Lansoprazole was subjected to di...

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Bibliographic Details
Main Authors: K. S. V Srinivas, K. Mukkanti, R. Buchi Reddy, P. Srinivasulu
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/304315