The effects of crocetin, extracted from saffron, in chemotherapy against the incidence of multiple drug resistance phenotype

Objective(s): Crocetin, one of the main substances of saffron extract, has anti-cancer effects. Drug resistance proteins (e.g. MRP1 and MRP2) are important reasons for the failure of cancer therapy. We intended to investigate the efficacy of crocetin on MRP1 and MRP2 activity in human ovarian cispla...

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Bibliographic Details
Main Authors: Navid Neyshaburinezhad, Maryam Hashemi, Mohammad Ramezani, Sepideh Arabzadeh, Javad Behravan, Fatemeh Kalalinia
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
MRP
Online Access:http://ijbms.mums.ac.ir/article_11612_133836ee9eac44219388142450d1cf73.pdf