Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase SignalingSummary
Background & Aims: Most targeted therapies against cancer are designed to block growth factor–stimulated oncogenic growth. However, response rates are low, and resistance to therapy is high. One mechanism might relate to the ability of tumor cells to induce growth factor–independent proliferatio...
Main Authors: | Jianliang Zhang, Irwin H. Gelman, Eriko Katsuta, Yuanzi Liang, Xue Wang, Jun Li, Jun Qu, Li Yan, Kazuaki Takabe, Steven N. Hochwald |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Cellular and Molecular Gastroenterology and Hepatology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X19300256 |
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