Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase SignalingSummary

Background & Aims: Most targeted therapies against cancer are designed to block growth factor–stimulated oncogenic growth. However, response rates are low, and resistance to therapy is high. One mechanism might relate to the ability of tumor cells to induce growth factor–independent proliferatio...

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Bibliographic Details
Main Authors: Jianliang Zhang, Irwin H. Gelman, Eriko Katsuta, Yuanzi Liang, Xue Wang, Jun Li, Jun Qu, Li Yan, Kazuaki Takabe, Steven N. Hochwald
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300256