Lychee Seed Fraction Inhibits Aβ(1-42)-Induced Neuroinflammation in BV-2 Cells via NF-κB Signaling Pathway

Lychee Seed Fraction Inhibits Aβ(1-42)-Induced Neuroinflammation in BV-2 Cells via NF-κB Signaling Pathway

In our previous studies, an active fraction derived from lychee seed could inhibit β-amyloid-induced apoptosis of PC12 cells and neurons. The primarily microglia cells are recognized as the brain’s resident macrophages and thought to remodel of the brain by removing presumably redundant, apoptotic n...

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Bibliographic Details
Main Authors: Ya Zhao, Yuan Zeng, Anguo Wu, Chonglin Yu, Yong Tang, Xiuling Wang, Rui Xiong, Haixia Chen, Jianming Wu, Dalian Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
lychee seed
Alzheimer’s disease
anti-neuroinflammation
Aβ(1-42)
NF-κB
Bcl-2
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00380/full

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