The importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogens.

BACKGROUND:Robust protocols for the isolation of extracellular vesicles (EVs) from the rest of their excretory-secretory products are necessary for downstream studies and application development. The most widely used purification method of EVs for helminth pathogens is currently differential centrif...

Full description

Bibliographic Details
Main Authors: Chelsea N Davis, Helen Phillips, John J Tomes, Martin T Swain, Toby J Wilkinson, Peter M Brophy, Russell M Morphew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6411213?pdf=render