Anillin propels myosin-independent constriction of actin rings

Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates contractile force in lieu of a molecular motor.

Bibliographic Details
Main Authors: Ondřej Kučera, Valerie Siahaan, Daniel Janda, Sietske H. Dijkstra, Eliška Pilátová, Eva Zatecka, Stefan Diez, Marcus Braun, Zdenek Lansky
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24474-1

Similar Items