Are we ready to design oral PROTACs®?

PROTACs® are expected to strongly impact the future of drug discovery. Therefore, in this work we firstly performed a statistical study to highlight the distribution of E3 ligases and POIs collected in PROTAC-DB, the main online database focused on degraders. Moreover, since the emerging technology...

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Bibliographic Details
Main Authors: Diego Garcia Jimenez, Matteo Rossi Sebastiano, Giulia Caron, Giuseppe Ermondi
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2021-08-01
Series:ADMET and DMPK
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/1037