NGF is an essential survival factor for bronchial epithelial cells during respiratory syncytial virus infection.
BACKGROUND:Overall expression of neurotrophins in the respiratory tract is upregulated in infants infected by the respiratory syncytial virus (RSV), but it is unclear where (structural vs. inflammatory cells, upper vs. lower airways) and why, these changes occur. We analyzed systematically the expre...
Main Authors: | Sreekumar Othumpangat, Laura F Gibson, Lennie Samsell, Giovanni Piedimonte |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2715860?pdf=render |
Similar Items
-
MicroRNA-221 modulates RSV replication in human bronchial epithelium by targeting NGF expression.
by: Sreekumar Othumpangat, et al.
Published: (2012-01-01) -
Vertical transmission of respiratory syncytial virus modulates pre- and postnatal innervation and reactivity of rat airways.
by: Giovanni Piedimonte, et al.
Published: (2013-01-01) -
Pathophysiological mechanisms for the respiratory syncytial virus-reactive airway disease link
by: Piedimonte Giovanni
Published: (2002-06-01) -
Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival
by: Sreekumar Othumpangat, et al.
Published: (2017-04-01) -
Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells.
by: Manuel Mata, et al.
Published: (2013-01-01)