Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway

Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway

<p>Abstract</p> <p>Background</p> <p>Trop2 is a cell-surface glycoprotein overexpressed by a variety of epithelial carcinomas with reported low to restricted expression in normal tissues. Expression of Trop2 has been associated with increased tumor aggressiveness, metas...

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Bibliographic Details
Main Authors: Cubas Rafael, Zhang Sheng, Li Min, Chen Changyi, Yao Qizhi
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/253

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