Novel Approaches to Epigenetic Therapies: From Drug Combinations to Epigenetic Editing

Novel Approaches to Epigenetic Therapies: From Drug Combinations to Epigenetic Editing

Cancer development involves both genetic and epigenetic alterations. Aberrant epigenetic modifications are reversible, allowing excellent opportunities for therapeutic intervention. Nowadays, several epigenetic drugs are used worldwide to treat, e.g., myelodysplastic syndromes and leukemias. However...

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Bibliographic Details
Main Authors: Aleksandra Majchrzak-Celińska, Anna Warych, Mikołaj Szoszkiewicz
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
epigenetic therapy
DNMT inhibitors
HDAC inhibitors
epigenetic editing
drug combinations
oncometabolites
Online Access:https://www.mdpi.com/2073-4425/12/2/208

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