Atg5-independent sequestration of ubiquitinated mycobacteria.

Like several other intracellular pathogens, Mycobacterium marinum (Mm) escapes from phagosomes into the host cytosol where it can polymerize actin, leading to motility that promotes spread to neighboring cells. However, only approximately 25% of internalized Mm form actin tails, and the fate of the...

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Bibliographic Details
Main Authors: Cathleen A Collins, Ann De Mazière, Suzanne van Dijk, Fredric Carlsson, Judith Klumperman, Eric J Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2673685?pdf=render