A genome-wide analysis of FRT-like sequences in the human genome.

Efficient and precise genome manipulations can be achieved by the Flp/FRT system of site-specific DNA recombination. Applications of this system are limited, however, to cases when target sites for Flp recombinase, FRT sites, are pre-introduced into a genome locale of interest. To expand use of the...

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Bibliographic Details
Main Authors: Jeffry L Shultz, Eugenia Voziyanova, Jay H Konieczka, Yuri Voziyanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3063242?pdf=render