Protein velocity and acceleration from single-cell multiomics experiments

Protein velocity and acceleration from single-cell multiomics experiments

Abstract The simultaneous quantification of protein and RNA makes possible the inference of past, present, and future cell states from single experimental snapshots. To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that le...

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Bibliographic Details
Main Authors: Gennady Gorin, Valentine Svensson, Lior Pachter
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Genome Biology
Subjects:
Protein acceleration
Protein velocity
RNA velocity
Transcriptomics
Multiomics
Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s13059-020-1945-3

Internet

http://link.springer.com/article/10.1186/s13059-020-1945-3

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