An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities.

Ikaros DNA binding factor plays critical roles in lymphocyte development. Changes in Ikaros expression levels during lymphopoiesis are controlled by redundant but also unique regulatory elements of its locus that are critical for this developmental process. We have recently shown that Ikaros binds i...

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Bibliographic Details
Main Authors: Elizabeth A Perotti, Katia Georgopoulos, Toshimi Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4489883?pdf=render