Topical Sucralfate Versus Hydrocortisone Cream In The Management Of Diaper Dermatitis : A Randomized, Doubleblind Clinical Trial

• Main Authors: Iraji Fariba, Kiyani Asadolah, Rezazadeh Marzieh
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2004-01-01
• Series: Indian Journal of Dermatology
• Online Access: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=4;spage=181;epage=183;aulast=Iraji;type=0

Topical corticosteroids are currently used for treatment of diaper dermatitis. Previous studies have shown the efficacy of sucralfate in the treatment of diaper dermatitis and contact dermatitis in peri-stomal areas. To evaluate the efficacy of topical sucralfate in comparison with hydrocortisone cream in the treatment of diaper dermatitis, the present study was under taken. In a double â€"blind randomized clinical trial, 64 patients with diaper dermatitis were treated with sucralfate cream 4% or hydrocortisone cream randomly. The duration of the treatment wad 8 weeks and the patients were evaluated every two weeks until complete healing. The results were evaluated by chi-square test. Complete healing (more than 50% improvement) occurred in 90.6% and partial healing (20-25% improvement) in rest of the patients in each group (p>0.05). Topical sucralfate is an effective, cheap therapeutic intervention for diaper dermatitis. Which has equal efficacy with topical hydrocortisone cream.