Characterization of the Recognition Specificity of BH2, a Monoclonal Antibody Prepared against the HLA-B27 Heavy Chain

Characterization of the Recognition Specificity of BH2, a Monoclonal Antibody Prepared against the HLA-B27 Heavy Chain

BH2, a monoclonal antibody prepared against the denatured human leukocytic antigen-B27 heavy chain (HLA-B27 HC), can immunoprecipitate the misfolded HLA-B27 HC complexed with Bip in the endoplasmic reticulum and recognize the homodimerized HLA-B27 HC that is often observed on the cell membrane of pa...

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Bibliographic Details
Main Authors: Hui-Chun Yu, Kuang-Yung Huang, Ming-Chi Lu, Hsien-Lu Huang, Wei-Ting Liu, Wen-Chien Lee, Su-Qin Liu, Hsien-Bin Huang, Ning-Sheng Lai
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:International Journal of Molecular Sciences
Subjects:
HLA-B27
ankylosing spondylitis
monoclonal antibody
HLA-typing
Online Access:http://www.mdpi.com/1422-0067/16/4/8142

Internet

http://www.mdpi.com/1422-0067/16/4/8142

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