Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors

Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors

<p>Abstract</p> <p>Background</p> <p>The treatment of human cancer has been seriously hampered for decades by resistance to chemotherapeutic drugs. Mechanisms underlying this resistance are far from being entirely known. A very efficient mechanism of tumor resistance to...

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Bibliographic Details
Main Authors: Spugnini Enrico P, Baldi Alfonso, Buglioni Sabrina, Carocci Francesca, Milesi de Bazzichini Giulia, Betti Gianluca, Pantaleo Ilaria, Menicagli Francesco, Citro Gennaro, Fais Stefano
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Translational Medicine
Subjects:
chemotherapy
lansoprazole
mitoxantrone
carboplatin
proton pump
Online Access:http://www.translational-medicine.com/content/9/1/221

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