Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy.

BACKGROUND:Mesenchymal progenitor cells (MPCs) have been isolated from a variety of connective tissues, and are commonly called "mesenchymal stem cells" (MSCs). A stem cell is defined as having robust clonal self-renewal and multilineage differentiation potential. Accordingly, the term &qu...

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Bibliographic Details
Main Authors: Rahul Sarugaser, Lorraine Hanoun, Armand Keating, William L Stanford, John E Davies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2714967?pdf=render