Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

Abstract Background Acquired drug resistance is a constraining factor in clinical treatment of glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire therapeutic resistance remain poorly understood. Here, we aim to investigate whether temozolomide (TMZ) resistance of chemoresp...

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Bibliographic Details
Main Authors: Zhuoran Zhang, Jianxing Yin, Chenfei Lu, Yutian Wei, Ailiang Zeng, Yongping You
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Exosomes
LncRNA-SBF2-AS1
Temozolomide-resistance
Glioblastoma
Online Access:http://link.springer.com/article/10.1186/s13046-019-1139-6

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