p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI)

p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI)

<p>Abstract</p> <p>Background</p> <p>Neuropathic pain is detrimental to human health; however, its pathogenesis still remains largely unknown. Overexpression of pain-associated genes and increased nociceptive somato-sensitivity are well observed in neuropathic pain. The...

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Bibliographic Details
Main Authors: Zhu Xiao-Yan, Huang Chang-Sheng, Li Qian, Chang Rui-min, Song Zong-bing, Zou Wang-yuan, Guo Qu-Lian
Format: Article
Language:English
Published: SAGE Publishing 2012-11-01
Series:Molecular Pain
Subjects:
Neuropathic pain
p300
COX-2
Acetyltransferase activity
CCI
Online Access:http://www.molecularpain.com/content/8/1/84

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