Identification of the thistle milk component Silibinin(A) and Glutathione-disulphide as potential inhibitors of the pancreatic lipase: Potential implications on weight loss

Identification of the thistle milk component Silibinin(A) and Glutathione-disulphide as potential inhibitors of the pancreatic lipase: Potential implications on weight loss

Peripheral targets like pancreatic-lipase appear to be the most suitable pharmacological alternative for obesity, as with orlistat, although its adverse effects limit its use. Therefore, the aim of this work was to identify new natural compounds able to inhibit pancreatic-lipase in an in vitro model...

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Bibliographic Details
Main Authors: Teresa Del Castillo-Santaella, Juan José Hernández-Morante, Jesús Suárez-Olmos, Julia Maldonado-Valderrama, Jorge Peña-García, Carlos Martínez-Cortés, Horacio Pérez-Sánchez
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Functional Foods
Subjects:
Pancreatic lipase
Silibinin(A)
Obesity
Lipolysis
Emulsion
Interfacial tension
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621001286

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