Digital Gangrene in Association with Retinoblastoma

We report a 5-year old boy, diagnosed with Retinoblastoma (RB) in the right eye and subsequently developed digital gangrene as a result of Raynaud’s phenomenon. Color Doppler ultrasound showed occlusion of radial and ulnar arteries of the left upper limb. Antinuclear Antibody, Antiphospholipid Antib...

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Bibliographic Details
Main Authors: Sarthak Das, Barath Jagadisan, Niranjan Biswal, Sriram Krishnamurthy, Subashini Kaliaperumal
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/11319/32445_F(AnG)_PF1(AJ_SHU)_PFA(AJ_SL)_PB(AJ_AP)_PN(AP).pdf
Description
Summary:We report a 5-year old boy, diagnosed with Retinoblastoma (RB) in the right eye and subsequently developed digital gangrene as a result of Raynaud’s phenomenon. Color Doppler ultrasound showed occlusion of radial and ulnar arteries of the left upper limb. Antinuclear Antibody, Antiphospholipid Antibody (APLA) and rheumatoid factors were negative. The patient was treated with low molecular weight heparin (enoxaparin), nifedipine, and analgesics. Raynaud’s syndrome and digital gangrene constitute a rare paraneoplastic process, which was not reported with retinoblastoma earlier.
ISSN:2249-782X
0973-709X