Silencing NUPR1 down-regulates autophagy and promotes migration and invasion in human multiple myeloma U266 cells

Silencing NUPR1 down-regulates autophagy and promotes migration and invasion in human multiple myeloma U266 cells

Objective To explore the effect of silencing nuclear protein 1 (NUPR1) on autophagy, migration and invasion in human multiple myeloma (MM) U266 cells and its possible mechanism. Methods NUPR1-shRNA was transfected into MM U266 cells, and the transfection rate was detected by flow cytometry. Then the...

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Bibliographic Details
Main Authors: LI Xingxin, LI Anmao, ZENG Chensi, CHEN Jianbin
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-12-01
Series:Di-san junyi daxue xuebao
Subjects:
nuclear protein 1
multiple myeloma
autophagy
migration
invasion
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201907123.htm

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