Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)Research in context
Background: Autosomal Recessive Polycystic Kidney Disease (ARPKD) is marked by cyst formation in the renal tubules, primarily in the collecting duct (CD) system, ultimately leading to end-stage renal disease. Patients with PKD are generally advised to restrict their dietary sodium intake. This study...
Main Authors: | Daria V. Ilatovskaya, Vladislav Levchenko, Tengis S. Pavlov, Elena Isaeva, Christine A. Klemens, Jessica Johnson, Pengyuan Liu, Alison J. Kriegel, Alexander Staruschenko |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-02-01
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Series: | EBioMedicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396419300064 |
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