Current Insights to Regulation and Role of Telomerase in Human Diseases

Current Insights to Regulation and Role of Telomerase in Human Diseases

The telomerase ribonucleoprotein complex has a pivotal role in regulating the proliferation and senescence of normal somatic cells as well as cancer cells. This complex is comprised mainly of telomerase reverse transcriptase (TERT), telomerase RNA component (TERC) and other associated proteins that...

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Bibliographic Details
Main Authors:	Mert Burak Ozturk, Yinghui Li, Vinay Tergaonkar
Format:	Article
Language:	English
Published:	MDPI AG 2017-02-01
Series:	Antioxidants
Subjects:	telomerase telomerase reverse transcriptase (TERT) hTERT promoter mutations telomerase RNA component (TERC) telomere cancer age-related diseases
Online Access:	http://www.mdpi.com/2076-3921/6/1/17

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