Aldose reductase: new insights for an old enzyme
In the past years aldose reductase (AKR1B1; AR) is thought to be involved in the pathogenesis of secondary diabetic complications such as retinopathy, neuropathy, nephropathy and cataractogenesis. Subsequently, several AR inhibitors have been developed and tested for diabetic complications. Although...
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Format: | Article |
Language: | English |
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De Gruyter
2011-04-01
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Series: | Biomolecular Concepts |
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Online Access: | https://doi.org/10.1515/bmc.2011.002 |