Aldose reductase: new insights for an old enzyme

In the past years aldose reductase (AKR1B1; AR) is thought to be involved in the pathogenesis of secondary diabetic complications such as retinopathy, neuropathy, nephropathy and cataractogenesis. Subsequently, several AR inhibitors have been developed and tested for diabetic complications. Although...

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Bibliographic Details
Main Author: Ramana Kota V.
Format: Article
Language:English
Published: De Gruyter 2011-04-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc.2011.002