DNA Methylation and the HOXC6 Paradox in Prostate Cancer

DNA Methylation and the HOXC6 Paradox in Prostate Cancer

Overexpression of the classical homeobox transcription factor HOXC6 is frequent in prostate cancers and correlates with adverse clinical parameters. Since surprisingly many HOXC6 target genes are downregulated in prostate cancer, it has been posited that oncogenic effects of HOXC6 in prostate cancer...

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Bibliographic Details
Main Authors: Wolfgang A. Schulz, Masanori Yamanaka, Anna Vinarskaja, Marc Ingenwerth
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Cancers
Subjects:
prostate cancer
epigenetic silencing
DNA methylation
homeobox transcription factors
WNT signaling
Online Access:http://www.mdpi.com/2072-6694/3/4/3714/

Internet

http://www.mdpi.com/2072-6694/3/4/3714/

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