Cytoprotective Effects of Punicalagin on Hydrogen–Peroxide–Mediated Oxidative Stress and Mitochondrial Dysfunction in Retinal Pigment Epithelium Cells

Cytoprotective Effects of Punicalagin on Hydrogen–Peroxide–Mediated Oxidative Stress and Mitochondrial Dysfunction in Retinal Pigment Epithelium Cells

The retinal pigment epithelium (RPE) is a densely pigmented, monostratified epithelium that provides metabolic and functional support to the outer segments of photoreceptors. Endogenous or exogenous oxidative stimuli determine a switch from physiological to pathological conditions, characterized by...

Full description

Bibliographic Details
Main Authors:	Maria Elisabetta Clementi, Giuseppe Maulucci, Giada Bianchetti, Michela Pizzoferrato, Beatrice Sampaolese, Giuseppe Tringali
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	Antioxidants
Subjects:	punicalagin ARPE–19 (human–RPE cell line) mitochondrion oxidative stress
Online Access:	https://www.mdpi.com/2076-3921/10/2/192

Similar Items

Punicalagin Protects Human Retinal Pigment Epithelium Cells from Ultraviolet Radiation-Induced Oxidative Damage by Activating Nrf2/HO-1 Signaling Pathway and Reducing Apoptosis
by: Maria Elisabetta Clementi, et al.
Published: (2020-06-01)

Relative Contribution of Different Mitochondrial Oxidative Phosphorylation Components to the Retinal Pigment Epithelium Barrier Function: Implications for RPE-Related Retinal Diseases
by: Michael H. Guerra, et al.
Published: (2021-07-01)

Effect of punicalagin on proliferation of porcine ovarian granulosa cells in vitro
by: Dagmara Packová, et al.
Published: (2016-12-01)

Physiological and Immune Functions of Punicalagin
by: Eva Venusova, et al.
Published: (2021-06-01)

Impact of Punicalagin on the Physicochemical and Structural Properties of Wheat Flour Dough
by: Hong Peng, et al.
Published: (2019-11-01)

Effect of punicalagin and human chorionic gonadotropin on body weight and reproductive traits in maiden rabbit does.
by: Anas A. Salem, Professor, et al.
Published: (2020-12-01)

Punicalagin Regulates Key Processes Associated with Atherosclerosis in THP-1 Cellular Model
by: Sanaa Almowallad, et al.
Published: (2020-11-01)

Punicalagin in Cancer Prevention—Via Signaling Pathways Targeting
by: Izabela Berdowska, et al.
Published: (2021-08-01)

Protective Effects of Punicalagin on Osteoporosis by Inhibiting Osteoclastogenesis and Inflammation via the NF-κB and MAPK Pathways
by: Wei Wang, et al.
Published: (2020-05-01)

Potential role of punicalagin against oxidative stress induced testicular damage
by: Faiza Rao, et al.
Published: (2016-01-01)

Punicalagin improves chorioallantoic and yolk sac vasculogenesis and teratogenesis of embryos induced by nicotine exposure
by: Chunmei Lin, et al.
Published: (2015-10-01)

Comparative Analysis of Gene Transfer to Human and Rat Retinal Pigment Epithelium Cell Line by a Combinatorial Use of Recombinant Adeno- Associated Virus and Ultrasound or/and Microbubbles
by: Xiao-Zhi Zheng, et al.
Published: (2009-08-01)

Punicalagin Mollifies Lead Acetate-Induced Oxidative Imbalance in Male Reproductive System
by: Faiza Rao, et al.
Published: (2016-08-01)

Evaluation of Natural Bioactive-Derived Punicalagin Niosomes in Skin-Aging Processes Accelerated by Oxidant and Ultraviolet Radiation
by: Mohamad EA, et al.
Published: (2021-07-01)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
by: Xin An, et al.
Published: (2020-05-01)

Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis
by: Kong J, et al.
Published: (2020-12-01)

In vitro and in vivo antioxidant activities of three major polyphenolic compounds in pomegranate peel: Ellagic acid, punicalin, and punicalagin
by: Yu-qing SUN, et al.
Published: (2017-08-01)

Evaluation of the In Vitro Oral Wound Healing Effects of Pomegranate (<i>Punica granatum</i>) Rind Extract and Punicalagin, in Combination with Zn (II)
by: Vildan Celiksoy, et al.
Published: (2020-08-01)

Inhibitory effects of punicalagin from Punica granatum against type II collagenase-induced osteoarthritis
by: Chia-Jung Lee, et al.
Published: (2018-02-01)

Punicalagin effect on total sleep deprivation memory deficit in male Wistar rats
by: Mohammad Nasehi, et al.
Published: (2021-03-01)

Transcriptomic analysis of Bursaphelenchus xylophilus treated by a potential phytonematicide, punicalagin
by: Qun-Qun Guo, et al.
Published: (2020-03-01)

Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
by: Mi Zhou, et al.
Published: (2020-06-01)

Herbosomes enhance the in vivo antioxidant activity and bioavailability of punicalagins from standardized pomegranate extract
by: A. Vora, et al.
Published: (2015-01-01)

Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5
by: Gulinigaer Anwaier, et al.
Published: (2021-06-01)

Antifungal potential of punicalagin against Cryptococcus neoformans species complex
by: Thaísa Cristina Silva, et al.
Published: (2018-10-01)

Clinical features of cases with retinal pigment epithelium aperture
by: Akie Yoshinaga, et al.
Published: (2021-06-01)

Protective mechanism of punicalagin against endoplasmic reticulum stress in the liver of mice with type 2 diabetes mellitus
by: Fang-fang Mo, et al.
Published: (2019-05-01)

Osmolarity and spectrophotometric property of brilliant blue green define the degree of toxicity on retinal pigment epithelial cells exposed to surgical endoilluminator
by: Balaiya S, et al.
Published: (2016-08-01)

Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2
by: Yohan Seo, et al.
Published: (2020-07-01)

A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy
by: Yuan Cao, et al.
Published: (2021-07-01)

Punicalagin Prevents Inflammation in LPS- Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway
by: Yuan Cao, et al.
Published: (2019-11-01)

Punicalagin Inhibited Inflammation and Migration of Fibroblast-Like Synoviocytes Through NF-κB Pathway in the Experimental Study of Rheumatoid Arthritis
by: Huang M, et al.
Published: (2021-05-01)

Pomegranate husk extract, punicalagin and ellagic acid inhibit fatty acid synthase and adipogenesis of 3T3-L1 adipocyte
by: Dan Wu, et al.
Published: (2013-04-01)

Supplementation with Hydroxytyrosol and Punicalagin Improves Early Atherosclerosis Markers Involved in the Asymptomatic Phase of Atherosclerosis in the Adult Population: A Randomized, Placebo-Controlled, Crossover Trial
by: Rebeca Quirós-Fernández, et al.
Published: (2019-03-01)

Punicalagin and ellagic acid from pomegranate peel induce apoptosis and inhibits proliferation in human HepG2 hepatoma cells through targeting mitochondria
by: Jia Li, et al.
Published: (2019-01-01)

The Punicalagin Metabolites Ellagic Acid and Urolithin A Exert Different Strengthening and Anti-Inflammatory Effects on Tight Junction-Mediated Intestinal Barrier Function In Vitro
by: Nina A. Hering, et al.
Published: (2021-03-01)

Optical coherence tomography and fundus autofluorescence findings in presumed congenital simple retinal pigment epithelium hamartoma
by: Baskaran, Prabu, et al.
Published: (2017-10-01)

Punicalagin Content and Antifungal Activity of Different Pomegranate (<i>Punica ganatum</i> L.) Genotypes
by: Domenico Rongai, et al.
Published: (2019-07-01)

Transcriptome Profiling of Embryonic Retinal Pigment Epithelium Reprogramming
by: Jared A. Tangeman, et al.
Published: (2021-05-01)

Photoreceptor degeneration in microphthalmia (Mitf) mice: partial rescue by pigment epithelium-derived factor
by: Yu Chen, et al.
Published: (2019-01-01)

Cannot write session to /tmp/vufind_sessions/sess_056f7a0olthvd20i69tmqvdp64