Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells

Free fatty acid release from fat cells, obtained from epididymal adipose tissue of rats of different sizes, was found to be dependent on the cell surface area, regardless of the age of the animals. The same result was found with cells of different sizes from the same animal. These results, when rela...

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Main Authors: OREN ZINDER, BENYAMIN SHAPIRO
Format: Article
Language:English
Published: Elsevier 1971-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520395511
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spelling doaj-742383aff28140d688b9e44b286f0cf72021-04-24T05:52:16ZengElsevierJournal of Lipid Research0022-22751971-01-011219195Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cellsOREN ZINDER0BENYAMIN SHAPIRO1Department of Biochemistry, The Hebrew University-Hadassah Medical School, Jerusalem, IsraelDepartment of Biochemistry, The Hebrew University-Hadassah Medical School, Jerusalem, IsraelFree fatty acid release from fat cells, obtained from epididymal adipose tissue of rats of different sizes, was found to be dependent on the cell surface area, regardless of the age of the animals. The same result was found with cells of different sizes from the same animal. These results, when related to in vivo conditions, would indicate that for the same adipose tissue mass, activity would decrease with increasing cell size. On the other hand, the total activity of a given tissue would increase by increasing the size of its cells.http://www.sciencedirect.com/science/article/pii/S0022227520395511lipolysiscell surface areaplasma membrane
collection DOAJ
language English
format Article
sources DOAJ
author OREN ZINDER
BENYAMIN SHAPIRO
spellingShingle OREN ZINDER
BENYAMIN SHAPIRO
Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
Journal of Lipid Research
lipolysis
cell surface area
plasma membrane
author_facet OREN ZINDER
BENYAMIN SHAPIRO
author_sort OREN ZINDER
title Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
title_short Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
title_full Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
title_fullStr Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
title_full_unstemmed Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
title_sort effect of cell size on epinephrine- and acth-induced fatty acid release from isolated fat cells
publisher Elsevier
series Journal of Lipid Research
issn 0022-2275
publishDate 1971-01-01
description Free fatty acid release from fat cells, obtained from epididymal adipose tissue of rats of different sizes, was found to be dependent on the cell surface area, regardless of the age of the animals. The same result was found with cells of different sizes from the same animal. These results, when related to in vivo conditions, would indicate that for the same adipose tissue mass, activity would decrease with increasing cell size. On the other hand, the total activity of a given tissue would increase by increasing the size of its cells.
topic lipolysis
cell surface area
plasma membrane
url http://www.sciencedirect.com/science/article/pii/S0022227520395511
work_keys_str_mv AT orenzinder effectofcellsizeonepinephrineandacthinducedfattyacidreleasefromisolatedfatcells
AT benyaminshapiro effectofcellsizeonepinephrineandacthinducedfattyacidreleasefromisolatedfatcells
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