Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells
Free fatty acid release from fat cells, obtained from epididymal adipose tissue of rats of different sizes, was found to be dependent on the cell surface area, regardless of the age of the animals. The same result was found with cells of different sizes from the same animal. These results, when rela...
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doaj-742383aff28140d688b9e44b286f0cf72021-04-24T05:52:16ZengElsevierJournal of Lipid Research0022-22751971-01-011219195Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cellsOREN ZINDER0BENYAMIN SHAPIRO1Department of Biochemistry, The Hebrew University-Hadassah Medical School, Jerusalem, IsraelDepartment of Biochemistry, The Hebrew University-Hadassah Medical School, Jerusalem, IsraelFree fatty acid release from fat cells, obtained from epididymal adipose tissue of rats of different sizes, was found to be dependent on the cell surface area, regardless of the age of the animals. The same result was found with cells of different sizes from the same animal. These results, when related to in vivo conditions, would indicate that for the same adipose tissue mass, activity would decrease with increasing cell size. On the other hand, the total activity of a given tissue would increase by increasing the size of its cells.http://www.sciencedirect.com/science/article/pii/S0022227520395511lipolysiscell surface areaplasma membrane |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
OREN ZINDER BENYAMIN SHAPIRO |
spellingShingle |
OREN ZINDER BENYAMIN SHAPIRO Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells Journal of Lipid Research lipolysis cell surface area plasma membrane |
author_facet |
OREN ZINDER BENYAMIN SHAPIRO |
author_sort |
OREN ZINDER |
title |
Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells |
title_short |
Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells |
title_full |
Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells |
title_fullStr |
Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells |
title_full_unstemmed |
Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells |
title_sort |
effect of cell size on epinephrine- and acth-induced fatty acid release from isolated fat cells |
publisher |
Elsevier |
series |
Journal of Lipid Research |
issn |
0022-2275 |
publishDate |
1971-01-01 |
description |
Free fatty acid release from fat cells, obtained from epididymal adipose tissue of rats of different sizes, was found to be dependent on the cell surface area, regardless of the age of the animals. The same result was found with cells of different sizes from the same animal. These results, when related to in vivo conditions, would indicate that for the same adipose tissue mass, activity would decrease with increasing cell size. On the other hand, the total activity of a given tissue would increase by increasing the size of its cells. |
topic |
lipolysis cell surface area plasma membrane |
url |
http://www.sciencedirect.com/science/article/pii/S0022227520395511 |
work_keys_str_mv |
AT orenzinder effectofcellsizeonepinephrineandacthinducedfattyacidreleasefromisolatedfatcells AT benyaminshapiro effectofcellsizeonepinephrineandacthinducedfattyacidreleasefromisolatedfatcells |
_version_ |
1721511578513178624 |