Phenotypic Analysis of Mutants of Ergosterol Biosynthesis Genes (ERG3 and ERG4) in the Red Yeast Xanthophyllomyces dendrorhous

Phenotypic Analysis of Mutants of Ergosterol Biosynthesis Genes (ERG3 and ERG4) in the Red Yeast Xanthophyllomyces dendrorhous

Xanthophyllomyces dendrorhous synthesizes astaxanthin, a carotenoid used in aquaculture. Astaxanthin is synthesized from metabolites of the mevalonate pathway, which are also precursors for sterols biosynthesis. The interruption of the CYP61 gene, which is involved in the synthesis of ergosterol (mu...

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Bibliographic Details
Main Authors: Maximiliano Venegas, Salvador Barahona, Ana María González, Dionisia Sepúlveda, Gustavo E. Zúñiga, Marcelo Baeza, Víctor Cifuentes, Jennifer Alcaíno
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
ergosterol
ERG3
ERG4
Xanthophyllomyces dendrorhous
carotenoids
sterol regulatory element-binding protein
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01312/full

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