Roquin is a major mediator of iron-regulated changes to transferrin receptor-1 mRNA stability

Summary: Transferrin receptor-1 (TfR1) has essential iron transport and proposed signal transduction functions. Proper TfR1 regulation is a requirement for hematopoiesis, neurological development, and the homeostasis of tissues including the intestine and muscle, while dysregulation is associated wi...

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Bibliographic Details
Main Authors: Victor M. Corral, Eric R. Schultz, Richard S. Eisenstein, Gregory J. Connell
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100328X