| Summary: | QUESTION: What is the current status of percutaneous coronary interventions to treat functional mitral regurgitation (MR)? ANSWER: Functional MR is one of the clinical conditions within cardiology that have experienced more changes over the last few years. Currently, not only the best way to treat it is under study including contributions from percutaneous techniques, but also its very definition is under review. Initially, cut-off values used to be selected to define its severity that were different from those of primary MR based on the results from longitudinal studies in populations that had suffered myocardial infarctions.1 However, it has not been easy to confirm that by using these diagnostic thresholds, the therapeutic procedures yield consistent benefits.2,3 As a matter of fact, to this date, it is recommended to use the same criteria as with primary MR (effective regurgitant orifice area ≥ 0.4 cm2 and regurgitant volume ≥ 60 mL).
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