E-p-Methoxycinnamoyl-α-l-rhamnopyranosyl Ester, a Phenylpropanoid Isolated from Scrophularia buergeriana, Increases Nuclear Factor Erythroid-Derived 2-Related Factor 2 Stability by Inhibiting Ubiquitination in Human Keratinocytes

E-p-Methoxycinnamoyl-α-l-rhamnopyranosyl Ester, a Phenylpropanoid Isolated from Scrophularia buergeriana, Increases Nuclear Factor Erythroid-Derived 2-Related Factor 2 Stability by Inhibiting Ubiquitination in Human Keratinocytes

The nuclear factor erythroid-derived 2-related factor 2 (Nrf2) is a key regulator of gene expression during oxidative stress and drug detoxification. Thus, identifying Nrf2 activators to protect from possible cell damage is necessary. In this study, we investigated whether E-p-methoxycinnamoyl-α-l-r...

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Bibliographic Details
Main Authors: Jiwon Jeong, Lilik Duwi Wahyudi, Young-Sam Keum, Heejung Yang, Jung-Hwan Kim
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
Nrf2
phenylpropanoid
antioxidant
ubiquination
Online Access:http://www.mdpi.com/1420-3049/23/4/768

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