Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved]
Polyphosphoinositides (PPIn) are essential signaling phospholipids that make remarkable contributions to the identity of all cellular membranes and signaling cascades in mammalian cells. They exert regulatory control over membrane homeostasis via selective interactions with cellular proteins at the...
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2019-03-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-278/v1 |
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doaj-73da47eeb9bd42e0977200f97edf4dcb2020-11-25T03:50:51ZengF1000 Research LtdF1000Research2046-14022019-03-01810.12688/f1000research.16679.118231Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved]Eamonn James Dickson0Department Physiology and Membrane Biology, University of California, Davis, CA, 95616, USAPolyphosphoinositides (PPIn) are essential signaling phospholipids that make remarkable contributions to the identity of all cellular membranes and signaling cascades in mammalian cells. They exert regulatory control over membrane homeostasis via selective interactions with cellular proteins at the membrane–cytoplasm interface. This review article briefly summarizes our current understanding of the key roles that PPIn play in orchestrating and regulating crucial electrical and chemical signaling events in mammalian neurons and the significant neuro-pathophysiological conditions that arise following alterations in their metabolism.https://f1000research.com/articles/8-278/v1 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Eamonn James Dickson |
| spellingShingle |
Eamonn James Dickson Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] F1000Research |
| author_facet |
Eamonn James Dickson |
| author_sort |
Eamonn James Dickson |
| title |
Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] |
| title_short |
Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] |
| title_full |
Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] |
| title_fullStr |
Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] |
| title_full_unstemmed |
Recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] |
| title_sort |
recent advances in understanding phosphoinositide signaling in the nervous system [version 1; referees: 3 approved] |
| publisher |
F1000 Research Ltd |
| series |
F1000Research |
| issn |
2046-1402 |
| publishDate |
2019-03-01 |
| description |
Polyphosphoinositides (PPIn) are essential signaling phospholipids that make remarkable contributions to the identity of all cellular membranes and signaling cascades in mammalian cells. They exert regulatory control over membrane homeostasis via selective interactions with cellular proteins at the membrane–cytoplasm interface. This review article briefly summarizes our current understanding of the key roles that PPIn play in orchestrating and regulating crucial electrical and chemical signaling events in mammalian neurons and the significant neuro-pathophysiological conditions that arise following alterations in their metabolism. |
| url |
https://f1000research.com/articles/8-278/v1 |
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