Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

Selection of inhibitor-resistant viral mutants is universal for viruses that display quasi-species dynamics, and hepatitis C virus (HCV) is no exception. Here we review recent results on drug resistance in HCV, with emphasis on resistance to the newly-developed, directly-acting antiviral agents, as...

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Bibliographic Details
Main Authors: Celia Perales, Josep Quer, Josep Gregori, Juan Ignacio Esteban, Esteban Domingo
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Viruses
Subjects:
viral quasi-species
hepatitis C virus
viral resistance
antiviral treatment
Online Access:http://www.mdpi.com/1999-4915/7/11/2902

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