Development of an experimental model to study the relationship between day-to-day variability in blood pressure and aortic stiffness

Development of an experimental model to study the relationship between day-to-day variability in blood pressure and aortic stiffness

We aimed to develop an animal model of long-term blood pressure variability (BPV) and to investigate its consequences on aortic damage. We hypothesized that day-to-day BPV produced by discontinuous treatment of spontaneously hypertensive rats (SHR) by valsartan may increase arterial stiffness. For t...

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Bibliographic Details
Main Authors: Camille eBouissou-Schurtz, George eLindesay, Veronique eRegnault, Sophie eRenet, Michel E. Safar, Vincent eMolinie, Hubert eDabire, Yvonnick eBezie
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Physiology
Subjects:
Telemetry
blood pressure variability
fibronectin
pulse wave velocity
Spontaneously Hypertensive Rat (SHR)
systolic blood pressure
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00368/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00368/full

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