Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles.

Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles.

We posit that the same mononuclear phagocytes (MP) that serve as target cells and vehicles for a host of microbial infections can be used to improve diagnostics and drug delivery. We also theorize that physical and biological processes such as particle shape, size, coating and opsonization that affe...

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Bibliographic Details
Main Authors: Arnaud Beduneau, Zhiya Ma, Cassi B Grotepas, Alexander Kabanov, Barrett E Rabinow, Nan Gong, R Lee Mosley, Huanyu Dou, Michael D Boska, Howard E Gendelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2629545?pdf=render

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