Human Microbiome Engineering: The Future and Beyond
Microbial flora of skin and mucosal surface are vital component of human biology. Current research indicates that this microbial constellation, rather than being inert commensals, has greater implications in health and disease. They play essential role in metabolism, immunity, inflammation, neuro-...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2015-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/6570/14946_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Microbial flora of skin and mucosal surface are vital component of human biology. Current research indicates that this microbial
constellation, rather than being inert commensals, has greater implications in health and disease. They play essential role in metabolism,
immunity, inflammation, neuro-endocrine regulation and even moderate host response to cancer. Genetic engineering was a major
breakthrough in medical research in 1970's and it opened up newer dimensions in vaccinology, large-scale synthesis of bio-molecule
and drug development. Engineering human microbiome is a novel concept. Recombinant DNA technology can be employed to modify
the genome of critical components of resident microflora to achieve unprecedented goals. |
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| ISSN: | 2249-782X 0973-709X |