Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease.
The present study was designed to examine the effects of ginsenoside Rg1 on expression of peroxisome proliferator-activated receptor γ (PPARγ) and insulin-degrading enzyme (IDE) in the hippocampus of rat model of Alzheimer's disease (AD) to determine how ginsenoside Rg1 (Rg1) decreases Aβ level...
Main Authors: | QianKun Quan, Jue Wang, Xi Li, Yi Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3592813?pdf=render |
Similar Items
-
Neuroprotective Effect of the Ginsenoside Rg1 on Cerebral Ischemic Injury In Vivo and In Vitro Is Mediated by PPARγ-Regulated Antioxidative and Anti-Inflammatory Pathways
by: Yang Li, et al.
Published: (2017-01-01) -
Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells
by: Yuheon Chung, et al.
Published: (2018-11-01) -
Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
by: Padmanaban Mohanan, et al.
Published: (2018-04-01) -
Study on Separation of Ginsenoside Rg1 and Ginsenoside Rb1 from Panax Notoginseng.
by: HO,TA-CHIH, et al.
Published: (2017) -
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
by: Jiahong Zhu, et al.
Published: (2014-01-01)