Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.

Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.

Induced pluripotent stem cells (iPSCs) have tremendous potential as a tool for disease modeling, drug testing, and other applications. Since the generation of iPSCs "captures" the genetic history of the individual cell that was reprogrammed, iPSC clones (even those derived from the same in...

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Bibliographic Details
Main Authors: Cheng Li, Jeffery M Klco, Nichole M Helton, Daniel R George, Jacqueline L Mudd, Christopher A Miller, Charles Lu, Robert Fulton, Michelle O'Laughlin, Catrina Fronick, Richard K Wilson, Timothy J Ley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370741?pdf=render

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