The role of D-serine as co-agonist of NMDA receptors in the nucleus accumbens: relevance to cocaine addiction

Cocaine addiction is characterized by compulsive drug use despite adverse consequences and high rate of relapse during periods of abstinence. Increasing consensus suggests that addiction to drugs of abuse usurps learning and memory mechanisms normally related to natural rewards, ultimately producing...

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Bibliographic Details
Main Authors: Marcello eD'Ascenzo, Maria Vittoria Podda, Claudio eGrassi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2014.00016/full