Analgesic effects of intra-articular fentanyl, pethidine and dexamethasone after knee arthroscopic surgery

• Main Authors: H Saryazd, P Kashefi, M Heydari, A Kiani
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2006-07-01
• Series: Journal of Research in Medical Sciences
• Online Access: http://journals.mui.ac.ir/jrms/article/view/315
• ISSN: 1735-1995; 1735-7136

BACKGROUND: Many different methods have been used in an effort to provide adequate analgesia after knee arthroscopic surgery. In this study analgesic effect of intra-articular fentanyl, pethidine and dexamethasone was compared.
 METHODS: In a double blind randomized study 48 male patients undergoing knee arthroscopic meniscectomy were allocated to groups receiving intra-articular fentanyl 50 µg or pethidine 20 mg or dexamethasone 8 mg at the end of arthroscopy during general aesthesia. Postoperative pain scores using visual analogue scale were measured and also analgesic requirements and the time of ability to walk were recorded.
 RESULTS: Pain scores at one, two, six and 24 h after intra-articular injection were not significantly different for fentanyl and pethidine but were higher significantly for dexamethasone at all four mentioned times. The mean average time of ability to walk was significantly longer for dexamethasone. The analgesic requirements during the first 24 h after intraarticular injection were significantly greater only for dexamethasone too.
 CONCLUSION: Better postoperative analgesia, less pain score and shorter time to walk were achieved by fentanyl and pethidine in comparison to dexamethasone but the results were not significantly different between fentanyl group and pethidine.
 KEYWORDS: Arthroscopy, opioid, pain.