Interleukin-27 Functional Duality Balances Leishmania Infectivity and Pathogenesis

Interleukin-27 Functional Duality Balances Leishmania Infectivity and Pathogenesis

IL-27 is a cytokine that exerts diverse effects on the cells of innate and adaptive immune systems. Chiefly expressed in macrophages and dendritic cells during the early phase of Leishmania infection, IL-27 contributes to the protection against L. major infection but suppresses the protective Th1 re...

Full description

Bibliographic Details
Main Authors: Abdollah Jafarzadeh, Maryam Nemati, Prashant Chauhan, Ashok Patidar, Arup Sarkar, Iraj Sharifi, Bhaskar Saha
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
EBI3
IL-27
Leishmania
p28
WSX-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01573/full

Similar Items

Similar Items