The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections.

The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections.

Immunity to Plasmodium falciparum (Pf) malaria is only acquired after years of repeated infections and wanes rapidly without ongoing parasite exposure. Antibodies are central to malaria immunity, yet little is known about the B-cell biology that underlies the inefficient acquisition of Pf-specific h...

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Main Authors: Greta E Weiss, Boubacar Traore, Kassoum Kayentao, Aissata Ongoiba, Safiatou Doumbo, Didier Doumtabe, Younoussou Kone, Seydou Dia, Agnes Guindo, Abdramane Traore, Chiung-Yu Huang, Kazutoyo Miura, Marko Mircetic, Shanping Li, Amy Baughman, David L Narum, Louis H Miller, Ogobara K Doumbo, Susan K Pierce, Peter D Crompton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2873912?pdf=render

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