Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironmentResearch in context

Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironmentResearch in context

Background: Glioblastoma (GBM), a highly malignant brain tumor, invariably recurs after therapy. Quiescent GBM cells represent a potential source of tumor recurrence, but little is known about their molecular underpinnings. Methods: Patient-derived GBM cells were engineered by CRISPR/Cas9-assisted k...

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Bibliographic Details
Main Authors: Rut Tejero, Yong Huang, Igor Katsyv, Michael Kluge, Jung-Yi Lin, Jessica Tome-Garcia, Nicolas Daviaud, Yuanshuo Wang, Bin Zhang, Nadejda M. Tsankova, Caroline C. Friedel, Hongyan Zou, Roland H. Friedel
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302099

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