A microRNA-based gene dysregulation pathway in Huntington's disease

Huntington's disease (HD) is a dominantly-inherited neurodegenerative disorder which is incurable and ultimately fatal. HD is characterised by widespread mRNA dysregulation, particularly in neurons of the forebrain, by mechanisms which are not fully understood. Such dysregulation has been demon...

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Bibliographic Details
Main Authors: Rory Johnson, Chiara Zuccato, Nikolai D. Belyaev, Deborah J. Guest, Elena Cattaneo, Noel J. Buckley
Format: Article
Language:English
Published: Elsevier 2008-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107002471