Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes[S]

Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes[S]

The lipid droplet-associated fat specific protein 27 (FSP27) suppresses lipolysis and thereby enhances triglyceride accumulation in adipocytes. We and others have recently found FSP27 to be a remarkably short-lived protein (half-life, 15 min) due to its rapid ubiquitination and proteasomal degradati...

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Bibliographic Details
Main Authors: Srijana Ranjit, Emilie Boutet, Pallavi Gandhi, Matthieu Prot, Yoshikazu Tamori, Anil Chawla, Andrew S. Greenberg, Vishwajeet Puri, Michael P. Czech
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Journal of Lipid Research
Subjects:
catecholamine
cytokine
FSP27
lipid droplets
protein stability
ubiquitination
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520405176

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http://www.sciencedirect.com/science/article/pii/S0022227520405176

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